Patterns of cellular proliferation during thyroid organogenesis
نویسندگان
چکیده
منابع مشابه
Patterns of cellular proliferation during thyroid organogenesis.
The changes in rate and location of cellular proliferation were analyzed to determine if localized areas of cell division were influencing shape changes in the chick thyroid. Pulse labeling with tritiated thymidine indicates that the gland's labeling index declines throughout its development. Initially, the thyroid placode has a lower labeling index than the neighboring pharyngeal epithelium. A...
متن کاملEvidence that thyroid hormone induces olfactory cellular proliferation in salmon during a sensitive period for imprinting.
Salmon have long been known to imprint and home to natal stream odors, yet the mechanisms driving olfactory imprinting remain obscure. The timing of imprinting is associated with elevations in plasma thyroid hormone levels, with possible effects on growth and proliferation of the peripheral olfactory system. Here, we begin to test this idea by determining whether experimentally elevated plasma ...
متن کاملSpatiotemporal patterns of multipotentiality in Ptf1a-expressing cells during pancreas organogenesis and injury-induced facultative restoration.
Pancreatic multipotent progenitor cells (MPCs) produce acinar, endocrine and duct cells during organogenesis, but their existence and location in the mature organ remain contentious. We used inducible lineage-tracing from the MPC-instructive gene Ptf1a to define systematically in mice the switch of Ptf1a(+) MPCs to unipotent proacinar competence during the secondary transition, their rapid decl...
متن کاملExpression of Pbx1b during mammalian organogenesis
Mammalian Pbx genes (Pbx1-3) encode a family of TALE homeodomain proteins that function as transcriptional regulators in numerous cell types (Curr. Opin. Genet. Dev. 8 (1998) 423). The present study highlights distinctive features of Pbx1b expression during mouse embryonic development as a framework to understand its biological functions. Immunohistochemical analyses demonstrate extensive expre...
متن کاملEmbryonic expression of nm23 during mouse organogenesis.
Nonmetastatic (nm) 23 gene expression correlates inversely with metastatic potential in several rodent tumor model systems as well as in human infiltrating ductal breast and hepatocellular carcinomas. Since tumor cell invasion and metastasis involve many processes exhibited by normal cells during development, we investigated whether nm23 is expressed during mouse embryogenesis. Northern blot an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Development
سال: 1978
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.48.1.269